The normal method of cleaning validation paid little attention to the design of the cleaning parameters. Instead, additional emphasis was placed on cleaning validation routines.2 This generally intended no less than three cleansing trials and screening of extreme situations (such as the lowest possible detergent concentration), wash and rinse cycle

four. Mixtures are preparations where drug or medicine are in Resolution or suspension designed for oral administration.Tablets or sound dosage forms are swallowed with drinking water and milk, together with other suitable liquids. Other forms are formulated for chewed, swallowing, dissolved, and dispersed in water prior to administration. Some are